December 2006 – Page 2

OSTEOPOROSIS AND TREATMENT SIDE-EFFECTS * Jaw Osteonecrosis

THE GOOGLE SEARCH FOR FOSAMAX AND OTHERS BRINGS FORWARD MANY PAID ADVERTISING LAW FIRMS REGARDING LAWSUIT INVITATION AND CONSULTATION REGARDING THIS CONCERN.

WWW.CASTMD.COM LOOKED TO SEE IF THIS IS A PROBABILITY OR POSSIBILITY FOR LITIGATION AND JURY AWARD. WHAT DOES SOME OF THE LITERATURE SAY?

MANY COMMENTS ARE BEING MADE OF THE RISK OF TAKING OSTEOPOROSIS MEDICATION FOR PREVENTING BONE LOSS, AND REBUILDING BONE. MOST, IF NOT ALL OF THE CONTROVERSY IS RELATED TO JAW BONE LOSS, order Clomiphene online canada OSTEONECROSIS OF THE JAW. THE CONTROVERSY ALSO RELATES TO THE POSSIBILITY OF THE MEDICINES CALLED afoot "BIPHOSPHONATES" SUCH AS FOSAMAX, AREDIA, AND ZOMETA, AND POSSIBLY OTHERS.

OSTEONECROSIS OF THE JAW IS A DEVASTATING CONDITION. THE BONE LOOKS AND ACTS INFECTED. MOST CASES COME FROM THE ILL EFFECTS OF INFECTION DUE TO DENTAL PROBLEMS OR DENTAL SURGERIES. MANY CASES, IF NOT ALMOST ALL, COME FROM THE USE OF INTRAVENOUS USE OF THE MEDICINES, WITH CASES OF METASTATIC BONE CANCER.

MERCK PUBLISHED THEIR CONTROLLED TRIALS OF OVER 17,000 PATIENTS, WITH 10 YEARS' DATA USING FOSAMAX, SHOWING NO REPORTS OF ONJ. IN POST-MARKETING USE, MERCK ESTIMATES BY MARCH 31, 2006 THE CUMMULATIVE RISK FROM ALL SOURCES OF CAUSE WAS ESTIMATED AT LESS THAN 1/100,000 PATIENT-TREATMENT YEARS.

CURRENTLY, THE NATIONAL OSTEOPOROSIS FOUNDATION SEES THE RISK AS RARE IN PERSONS TAKING ANY ORAL FORM OF THE MEDICINE FOR OSTEOPOROSIS. THE FOUNDATION ALSO STATES THAT IT BELIEVES THAT THE RISK OF FRACTURES AND BONE LOSS IS MUCH GREATER TO MOST PATIENTS THAN ANY RISK OF DEVELOPING THE ONJ PROBLEM DUE TO THE MEDICINES FOR OSTEOPOROSIS.

PLEASE, IF YOU ARE ON A MEDICINE FOR REDUCTION OF OSTEOPOROSIS RISK, A BIPHOSPHONATE, TALK WITH YOUR DOCTOR AND STAY INFORMED. HOPEFULLY THIS HAS ASSISTED YOU IN YOUR DECISION TO BE AND STAY HEALTHY.

THE PRESTIGIOUS NEW ENGLAND JNL OF MED WILL SPEAK TO THE ISSUE THIS NEXT WEEK, I AM ANTICIPATING.

BABY BOOMER BREAKDOWN MEDICAL CLINIC & OXYGEN BAR *** A Health Screening Survey A MEDICAL PARODY

HEALTH SCREENING SURVEY

ARE YOUR HEMORRHOIDS HURTIN’ FROM TOO MUCH HARLEY RIDIN’

ARE YOU DRINKIN' MORE PRUNE JUICE THAN BEER

ARE YOU ASKIN' FOR DIRECTIONS CUZ YOU CAN’T SEE

ARE YOU PALPITATIN’ WHEN MAMA ISN’T EVEN THERE

ARE YOU CREAKIN’ MORE THAN THE FLOOR

ARE YOU BEDDIN’ DOWN BEFORE THE ‘LATE SHOW’

ARE YOU WONDERIN' ABOUT BUYIN’ THE RV

ARE YOU BUYIN' CROAKIES FOR YOUR READIN’ GLASSES

ARE YOU INVESTIN' IN FLAX AND FIBER COMPANIES

ARE YOU DRIBBLIN’ UNTIMELY INSTEAD OF BASKETBALLS

ARE YOU SHOPPIN’ WALMART AND GETTIN’ LOST

ARE YOU BORN BETWEEN '46 AND '64

IF YES

COME TO THE NEW AND UNIQUE

“BABY BOOMER BREAKDOWN

MEDICAL CLINIC & OXYGEN BAR”^©

(a select pathway)

(Based on the Vegas Oxygen Bars only with Medicare coverage)

YOU’LL LOVE THE TALKIN’

WITH LITTLE WALKIN’

SIP YOUR JUICE

AND PLAY SOME FOOS

NOT ONLY MEDICARE D CLASSES

BUT KENO AND LOTTO FOR THE MASSES

COME ONE COME ALL

BEFORE YOU TAKE THAT NEXT FALL

CALL FOR APPOINTMENTS NOW…BEFORE YOU FORGET

HEADACHE – MIGRAINE HELP YOUR DOCTOR HELP YOURSELF

MANY PATIENTS HAVE HEADACHES. SOME PATIENTS HAVE MIGRAINE HEADACHE. THERE ARE CONSENSUS INTERNATIONAL CRITERIA FOR MIGRAINE HEADACHE. THEY ARE:

RECURRENT, EPISODIC, LENGTH 4 TO 72 HOURS, QUALITY OF UNILATERAL OR THROBBING OR MOTION WORSENING OR MODERATE TO SEVERE RATING – MATCHED WITH NAUSEA, VOMITING, LIGHT-SENSITIVITY OR SOUND SENSITIVITY.

WORRISOME TYPES OF SYMPTOMS TO TELL YOUR DOCTOR ARE:

SYSTEMIC DISEASES SUCH AS DIABETES, NEUROLOGIC CONCERNS, SUDDEN ONSET, ONSET OVER 50 YEARS OLD OR UNDER 5 YEARS, PATTERN OF HEADACHE CHANGES.

OTHER THOUGHTS TO REVIEW BEFORE TALKING WITH YOUR DOCTOR ABOUT YOUR HEADACHE ARE THE FOLLOWING:

FIRST, WORST, FREQUENCY, DIFFERENCE, IMPROVED BY, WORSENED BY, ONSET, RADIATION, QUALITY OF PAIN, PAST MEDICAL HISTORY, CURRENT PRESCRIPTION DRUGS, OTC DRUGS, HERBALS, AND WHOLISTIC MEDS, ALONG WITH ANY INJURY OR TRAUMA BOTH RECENT OR IN THE PAST.

NEW MEDICINES EXIST FOR MIGRAINE HEADACHES BOTH FOR TREATMENT AND PREVENTION. TALK WITH YOUR DOCTOR ABOUT YOUR OPTIONS AND A PLAN OF ACTION.

BE HEADACHE FREE

COCAINE “ENERGY DRINK” IS CAFFEINE BASED – ALOT ! OVERDOSE potential ?

THE LASTEST CRAZE OF ENERGY DRINKS IS THIS PRODUCT BY REDUX BEVERAGES FROM LAS VEGAS. IT IS NOT COCAINE. IT IS CAFFEINE BASED. EACH UNIT HAS ABOUT 280 MG OF CAFFEINE. THE AVERAGE COFFEE CUP HAS ABOUT 80 MG.

THE QUESTION IS: IS IT UNETHICAL ADVERTISING TO HIGHLIGHT AND ENTICE THE "ABUSE" OF OVERUSE, OVERDOSE, AND GETTING HIGH WITH SUCH PRODUCTS?

CAFFEINE OVERDOSE IS A SERIOUS MATTER. MANY TIMES THE KIDS THAT RELY ON THE "HIGH" MAY ALSO BE ABUSING OTHER AGENTS OF TOXICITY.

SHOULD WE ADVERTISE THE "HIGH" OF SNIFFING PAINT, PAINT IS A LEGAL PRODUCT ?

SHOULD WE ADVERTISE THE "HIGH" OF HUFFING COMPUTER AIR, AIR IS A LEGAL PRODUCT?

SHOULD WE ADVERTISE THE "HIGH" OF ALCOHOL, ALCOHOL IS A LEGAL PRODUCT?

THE ANSWER IS THAT THIS PRODUCT AND OTHERS, I BELIEVE, HIGHLIGHT ABUSE AND OVERUSE.

TELLING A PARENT THAT THEIR SON OR DAUGHTER HAS DIED IN THE ER OR WAS D.O.A. IS A REAL EXPERIENCE THAT SOME OF US HAVE HAD TO BARE…

THE ANSWER IS: YES, IT IS UNETHICAL ADVERTISING AND MARKETING. THE COMPANIES SHOULD BE HELD RESPONSIBLE FOR THE "ENTICING" APPROACH.

DEATH BY CAFFEINE IS NOT ANY MORE CALMING THAN DEATH BY OTHER OVERDOSE MEANS. PARENTS BEWARE.

(adapted: aceommroupdt)

PHARMACEUTICAL COMPANIES AND ADVERTISING FOR ILLNESS

WITH THE RECENT EXPLOSION IN MASS MARKETING AND ADVERTISING FOR PHARMACEUTICAL MEDICINES AND ILLNESS, DO YOU THINK IT IS MORALLY AND ETHICALLY CORRECT?

WITH WWW.CASTMD.COM SHOWING THE RECENT EXPLOSION OF ONE EXAMPLE OF ILLNESS MADE PROFIT, MAYBE THE "OLD" DAYS OF PHARMA ADVERTISING SHOULD BE RETURNED. THAT IS – WHEN LIMITED ADS COULD BE RUN.

THUS THE QUESTION: SHOULD WE AS CONSUMERS BE BOMBARDED WITH ILLNESS ADS AND DRUG THERAPIES THAT MAY OR MAY NOT HELP? IT DOES CREATE HIGHER COSTS FOR THE MEDICINES THAT MANY PATIENTS NEED.

SOCIALIZED MEDICINE LIKE MEDICARE AND MEDICAID PROGRAMS WILL CONTINUE TO LIMIT ACCESS AND COSTS WITH SUCH BACK ROOM ADS GOING ON TO RUN UP COSTS AND USAGE.

VOTE IN THE CURRENT READER POLL IF YOU WISH.

DIARRHEA -TOXIC EPIDEMIC STRAIN – infection – diarrhea – ANTIBIOTIC OVERUSE ABUSE: DO YOU REALLY NEED THAT ANTIBIOTIC…DO YOU REALLY WANT IT ?

CLOSTRIDIUM DIFFICILE IS THE MOST COMMON IDENTIFIABLE REASON THAT PERSONS GET ANTIBIOTIC ASSOCIATED DIARRHEA (CDAD). THIS IS A GRAM POSITIVE ANAEROBIC BACILLUS.

THIS EMERGENCE OF A HIGHER TOXIC, MORE RESISTANT STRAIN (B1/NAP1) IS THOUGHT TO BE DUE TO THE WIDESPREAD USE OF FLOUROQUINOLONES, POTENT ANTIBIOTICS USED FOR LESS SERIOUS INFECTIONS AND EVEN VIRAL INFECTIONS, WHEN PATIENTS DO NOT REALLY NEED ANY ANTIBIOTIC. USE OF TIER TWO AND THREE CEPHALOSPORINS, AMPICILLIN, CLINDAMYCIN OR THE FLUROQUINOLONES HAVE LED THE PROBLEM OF CDAD.

JUST LIKE WITH METH OR OTHER "DOA" SKIN POPPING – MRSA (METHICILLIN RESISTANT STAPH A. INFECTIONS) CONTINUES TO PLAGUE THE INFECTIOUS DISEASE COMMUNITY AT ALL LEVELS.

SO HOW HAS THIS PROBLEM OF SEVERE DIARRHEA CHANGED?

IN THE PAST, JUST STOPPING THE ANTIBIOTIC WOULD STOP THE DIARRHEA IN A FEW DAYS. OVER THE PAST YEARS, WE HAD TO START TREATING THE INFECTIOUS DIARRHEA WITH ANOTHER ANTIBIOTIC TO KILL THE C. DIFF. BUG FROM THE BOWEL.

NOW, THE ROUTINE ANTIBIOTIC OF METRONIDAZOLE IS LIMITED IN ITS EFFECTIVENESS, THUS MAKING THE DOCTOR GO TO THE LAST RESORT ANTIBIOTIC OF VANCOMYCIN, A VERY STRONG, EXPENSIVE, AND POTENTIALLY DANGEROUS LAST RESORT.

WHAT CAN HAPPEN TO THE PATIENT? INITIALLY, BAD DIARRHEA. IF IT WORSENS, EVEN FULMINANT C. DIFF. ASSOCIATED DIARRHEA CAN BECOME TOXIC TO THE COLON, CAUSE SHOCK, AND EVEN COLON RUPTURE. AT THIS STAGE MORTALITY APPROACHES 50% OF PATIENTS.

THE CENTERS FOR DISEASE CONTROL (CDC) ARE EVEN RECOMMENDING THE VANCOMYCIN AS A FIRST LINE MED FOR SOME HOSPITALS FOR CERTAIN BACTERIA. NO ROOM TO WIGGLE HERE…

ABOUT 1/3 OF PATIENTS WITH ONE OCCURRENCE GET ADDITIONAL REOCCURENCES, THUS ACCELERATING THE PROBLEM OF LIMITED OR NO THERAPY LEFT IN THE DOCTOR'S MEDICAL BAG.

THUS THE STORY…TOO MUCH USE OF ALL ANTIBIOTICS HAS LED US DOWN THIS DANGEROUS PATH FOR PATIENTS. RECENTLY, A REPORT SUGGESTED WAITING A DAY OR TWO ON ALL ANTIBIOTICS FOR CHILDREN'S "RED EAR" POSSIBLE INFECTIONS. MANY ARE VIRAL.

ALL IN ALL, CAUTIOUS AND JUDICIOUS USE OF ALL ANTIBIOTICS IS A MUST. PATIENTS MUST ASSIST THEIR PHYSICIAN ON THE DECISION TO MAYBE CAUTIOUSLY WAIT…VERSUS THE DOCTOR VISIT MANTRA REQUESTING: "I WANT AN ANTIBIOTIC."